2000s

• 2000 Toyota Estima hybrid (Japanese market only)
• 2000 Toyota Prius US market
• 2002? Mazda Demio e-4WD (Japanese market only, used for traction assistance)
• 2002 New Flyer DE60LF (diesel-electric hybrid articulated bus)
• 2002 Dyna Diesel Hybrid (Japan only, Diesel Hybrid)
• 2002 Honda Civic Hybrid 2003 model

2003

• Renault Kangoo (plug-in hybrid electric vehicle)
• Suzuki Twin
• Toyota Alphard Hybrid
• Toyota Prius (5 seat midsize) 2004 model year, second generation Hybrid Synergy Drive

2004

• Honda Accord Hybrid 2005 model
• Ford Escape Hybrid 2005 model (released in late summer 2004)
• General Motors city bus

2005

• Chevrolet Silverado/GMC Sierra Hybrid 2006 model, Mild hybrid
• Honda Civic Hybrid 2006 model, second generation
• Lexus RX 400h 2006 model year, second generation Hybrid Synergy Drive
• Mercury Mariner hybrid
• Toyota Kluger/Highlander Hybrid 2006 model

2006

• Lexus GS 450h 2007 model, second generation Hybrid Synergy Drive
• Saturn VUE Green Line 2007 model, Mild hybrid
• Toyota Camry Hybrid 2007 model, second generation Hybrid Synergy Drive
• Toyota Estima/Previa hybrid minivan, second generation Hybrid Synergy Drive (Japanese market only)

2007

• Nissan Altima Hybrid (limited sales)
• Saturn Aura Green Line Hybrid (BAS) 2008 model, Mild hybrid